Specialty
Hematology and oncology
Work time
part-time
Start date
ab sofort
Employment period
limited
Application deadline
12.10.2026
Deployment location Charité
Campus Virchow-Klinikum, Wedding
Jobcode
7975
Salary group
E13
Working at Charité
The Penter Lab is a young and dynamic research group focused on understanding the complex interactions between leukemia and the immune system in the context of allogeneic hematopoietic cell transplantation.
Our research centers on a fundamental question: how do T cells recognize and eliminate leukemia, and how do leukemic cells evolve to escape immune surveillance? We investigate the biology, dynamics, and antigen specificities of leukemia-directed T cells, as well as mechanisms of immune resistance, including clonal evolution and adaptation under immune pressure.
Our long-term goal is to translate these insights into novel cellular therapies and innovative tools to monitor and understand immune responses and immune resistance in patients with hematologic malignancies.
We address these questions directly in primary patient-derived blood and bone marrow samples. Our research combines experimental immunology with state-of-the-art single-cell immunogenomics and deep, independent computational data analysis. This integrated approach allows us to track individual immune cell clones, characterize their T-cell receptors and antigen specificities, and investigate how leukemia–immune cell interactions evolve over the course of disease and treatment.
Overview of the position
Throughout the work on your PhD project you will utilize immunogenomics tools to identify minor histocompatibility antigens (miHAs) in recipients of allogeneic stem cell transplantation and identify donor T cells that recognize these miHAs. In particular, you will:
What we are looking for
We are looking for a highly motivated PhD candidate with an interest in combining wet and dry lab immunogenomics methods to study dynamics, phenotypes and specificities of leukemia-directed T cells. Your profile:
Charité offers you
Information regarding the position
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
For data protection reasons, we only accept applications via our application portal. The contact details provided below are intended solely for inquiries.
Apply nowIf you have questions, please contact:
PD Dr. med. Livius Penter
livius.penter@charite.de
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.