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Research associate / PhD (d/f/m) at the Research Lab of the Department of Endocrinology and Metabolism

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Research associate / PhD (d/f/m) at the Research Lab of the Department of Endocrinology and Metabolism

Specialty
Internal medicine

Charite Kampagne 1350x900 5 Entdeckung 1
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Work time
part-time

Start date
01.10.2025

Employment period
limited

Application deadline
29.08.2025

Deployment location Charité
Campus Charité Mitte

Jobcode
5264

Salary group
E13

 

Working at Charité

This subproject of the CRC/TR 412 investigates the development of metabolic dysfunction-associated steatotic liver disease (MASLD) in the context of the gut microbiome and nutrition. It focusses on longitudinal experiments in humanized gnotobiotic mice transplanted with stool samples from human subjects of a nutritional intervention studies. The animals are comprehensively metabolically phenotyped with a particular emphasis on liver metabolism and fatty liver development. This research enables a unique combination of a clinical study and animal experiments and aims to decipher microbiome-dependent mechanisms of MASLD pathogenesis. The long-term goal is to identify protective microbial strains that could serve as basis for new microbiome-based therapeutic approaches. The project is being carried out in close cooperation with Prof. Sofia Forslund-Startceva (ECRC and MDC), a leading expert in host-microbiome interactions and high-throughput bioinformatics.

Overview of the position

  • Performing experimental animal research with gnotobiotic mice with a focus on (liver) metabolism
  • Interdisciplinary collaboration within the CRC/TR 412 with working groups in microbiology, bioinformatics and hepatology
  • Application and further development of complex, innovative methods for phenotyping (e.g. metabolic tests, histological and molecular analyses)
  • Establishment, optimization and documentation of scientific protocols and experimental techniques in the field of microbiome and metabolic research
  • Sample processing, collection and analysis of material from clinical and mouse studies
  • Translational integration of animal experimental data with results from a clinical study
  • Presentation of research results at national and international conferences and publication in scientific journals
  • According to Section 110 BerlHG, the employee is provided with time for their own academic qualifications

What we are looking for

  • Master's degree (or equivalent) in (molecular) biology, biochemistry, pharmacology or a related field
  • Strong interest in interdisciplinary, clinically relevant questions in the field of microbiome-liver interaction, metabolic processes and (fatty) liver pathologies
  • Willingness to work with animal models (mouse) (experience/FELASA course advantageous)
  • Accurate and independent working style
  • High level of motivationand ability to think conceptually
  • Strong organizational and communication skills, reliability, creativity, flexibility
  • Scientific curiosity and the ability to work independently and in a team
  • Excellent English (written and spoken)

Charité offers you

  • Highly professional work environment in motivated and interdisciplinary teams
  • A future-oriented, varied and demanding position with a high grade of personal responsibility and personal decision making opportunities
  • Intercultural team events, well structured onboarding phase with kind team members
  • Extensive offers for inhouse training and professional development as well as further qualifications
  • Special offers in the areas of shopping, travel and sports
  • Additional pension program with a company wide pension scheme
  • Certification as a family friendly university and company since 2007 - You may find further information here

Information regarding the position

  • Paygrade E13 according to TVöD VKA-K. Your job grade depends on your job qualification whereas the experience level depends on the number of working years. The yearly gross salary is hereby provided based on a full time position excluding yearly bonus and additional pay. You may find further information here
  • Working hours: 25,03 per week 
  • The position is limited until 30.06.2029, as it is tied to the project duration
  • 30 days of paid vacation per year
  • The application period ends on: 29.08.2025
  • Position ID: 5264

Application

 

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.

Apply using our online tool and become part of the Charité.

Apply now

If you have questions, please contact:

Sebastian Brachs

sebastian.brachs@charite.de

030450514333

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.