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Postdoctoral Researcher - Department of Hepatology and Gastroenterology

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Postdoctoral Researcher - Department of Hepatology and Gastroenterology

Specialty
Gastroenterology, Hepatology

Charite Kampagne 1350x900 5 Entdeckung 1
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Work time
full-time

Start date
01.10.2025

Employment period
limited

Application deadline
05.09.2025

Deployment location Charité
Campus Virchow-Klinikum, Wedding

Jobcode
5244

Salary group
E13

 

Working at Charité

The Peiseler Lab at Charité – Universitätsmedizin Berlin is looking for a highly motivated and talented postdoctoral researcher to join our interdisciplinary team of immunologists, clinician scientists and bioinformatics  focused on liver immunology in chronic liver diseases. We have a keen interest in liver myeloid cells and leverage cutting-edge intravital microscopy to investigate liver immune cell behavior to uncover mechanisms of liver disease.

This position is part of the DFG-funded Transregio Collaborative Research Center CRC/TR 412, seeking to address the pathogenic mechanisms in Metabolic dysfunction-associated steatotic liver disease (MASLD) and brings together expertise from Charité Berlin, TU Dresden, MPI CBG Dresden, and the M3 Research Institute Tübingen. The successful candidate will work at Charité under joint supervision by Moritz Peiseler (Charité) and Robert Schwabe (Columbia University, New York). The project will investigate the reciprocal crosstalk of liver macrophages and hepatic stellate cells in the progression and regression of MASLD and fibrosis, utilizing novel mouse models, intravital multiphoton microscopy, and multi-omics technologies (single-cell and spatial transcriptomics).

You can find more information on our scientific mission here.

Overview of the position

  • Conduct research on metabolic liver injury and inflammation/fibrosis in MASLD
  • Perform mouse experiments using intravital microscopy
  • Analyze single-cell and spatial sequencing and multiplex immunostaining data from human and mouse samples
  • Develop innovative methods and concepts in MASLD research and collaborate with clinicians, bioinformaticians, systems biologists, and experimental researchers in a highly interdisciplinary setting
  • Contribute to the supervision of PhD students and junior researchers  
  • Prepare scientific publications and present results at national and international conferences
  • According to Section 110 (4), sentence 3 of the Berlin Higher Education Act (BerlHG), academic staff are entitled to an appropriate amount of time during working hours for their own academic further qualification

What we are looking for

  • A completed doctoral degree (PhD or equivalent) in bioinformatics, biology, biochemistry, systems biology, or a related discipline
  • Strong background in experimental biology, immunology, or hepatology
  • Interest in interdisciplinary teamwork within the CRC/TR 412 consortium
  • Enthusiasm for microscopy and image data analysis
  • Experience in analyzing multi-omics data (proteomics, metabolomics, and/or genomics, transcriptomics) with strong biological insight
  • Skills in statistical analysis, computational tools and programming are desirable
  • Experience with mouse models and in vivo experiments
  • Scientific curiosity and passion for addressing clinically relevant problems
  • Transparent and independent working style
  • Excellent English language proficiency and computer literacy
  • High-quality publication record

Charité offers you

Highlights of working in the CRC/ TR 412:

  • Prospects for long-term career development as a project leader within CRC/TR 412
  • Lab visits and scientific exchange with partner sites: Charité Berlin, TU Dresden, MPI CBG Dresden, and M3 Research Center Tübingen
  • Access to postgraduate training and education through the Berlin University Alliance (BUA)
  • Hands-on advanced methods courses featuring cutting-edge technologies
  • Retreats and networking events fostering collaboration and professional growth
  • Commitment to gender-aware research and a diverse, LGBTQ+ friendly, and family-supportive work environment
  • Life and research in the vibrant and culturally rich city of Berlin

Information regarding the position

  • Paygrade E13 according to TVöD VKA-K. Your job grade depends on your job qualification whereas the experience level depends on the number of working years. The yearly gross salary is hereby provided based on a full time position excluding yearly bonus and additional pay. You may find further information here
  • Working hours can be full-time with up to 38.5 hours per week
  • The position is limited until 30.06.2029, as it is tied to the project duration
  • 30 days of paid vacation per year
  • The application period ends on: 05.09.2025
  • Position ID: 5244

Application

 

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.

Apply using our online tool and become part of the Charité.

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If you have questions, please contact:

Dr. Moritz Peiseler (Projectleader): moritz.peiseler@charite.de

Dr. Katharina Detjen (Scientific Coordinator): katharina.detjen@charite.de or telephone: +49 30 450 559649

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.