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Research Associate (PhD student) Institute of Pathology DM.33.25

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Research Associate (PhD student) Institute of Pathology DM.33.25

Specialty
Pathology

Charite Kampagne 1350x900 2 Entdeckung Bildschirm
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Work time
part-time

Start date
ab sofort

Employment period
limited

Application deadline
28.02.2025

Deployment location Charité
Campus Charité Mitte

Jobcode
4361

Salary group
E13

 

Working at the Charité

The group of Dr. Frank Dubois is looking for highly motivated Research Associate (PhD candidates)  interested in investigating how cancer cells change the 3D genome to hijack gene regulation for aberrant expression of oncogenes from high-level genomic amplifications. The bioinformatics part of the project will involve whole genome sequencing and epigenetic analysis of several hundred tumor samples from breast and lung cancer patients.

Job Overview

The lab is a young group funded by a Max Eder Grant of the German Cancer Aid and is located at the Institute of Pathology at Charité Campus Mitte. We have extensive experience in both computational and experimental approaches. The successful applicant will work closely with an international and interdisciplinary group, including clinicians, bioinformaticians, and biologists. The environment provides many opportunities to learn new skills and we are deeply committed to excellent mentorship. A wealth of basic science and clinical collaborations in Berlin enable the pursuit of questions with translational potential. For more information please see www.duboislab.org.

Your responsibilities may include, but are not limited to, the following activities:

  • Analysis of sequencing data from short-read and long-read WGS, methylation, HiC, ATAC, ChIP, and RNAseq data starting from the raw data/ fastq files
  • Identify significantly recurrent genomic changes in cohorts of tumor samples, developing generalizable tools and pipelines in the process
  • Work with the other group members and collaborators in Berlin and other institutions across the world
  • Contribute to all levels of the research you are engaged including experimental design, data analysis, visualization, and writing
  • Scientific staff is given sufficient time to carry out their own scientific work in accordance with their employment relationship (in accordance with § 110 BerlHG)

Required:

  • MSc in Bioinformatics, Data Science, Computer Science, or Biostatistics similar. 
    - Experience in computational biology (sequencing and data analysis, machine learning)

  • Strong intrinsic motivation, scientific curiosity, organizational skills, and a strong interest in learning about novel technologies

  • Strong communication skills in written and spoken English

  • Being collaborative and proactive

     

  • We offer a friendly, collaborative, and fast-paced environment that strives for scientific excellence, investigating clinically impactful questions, and developing each of its team members. We also offer a chance to affiliate with the CompCancer grad school https://www.comp-cancer.de/ under co-supervision of Prof. Beule

Advantages at the Charité

  • A highly professional collaboration within a motivated and interdisciplinary team
  • A future-oriented, varied and challenging job with high levels of personal responsibility and personal freedom of action
  • Inter-cultural team events, well-structured onboarding with friendly colleagues
  • Extensive free continuing education and training opportunities up to and including university studies
  • Discounts on various offerings for employees, for example shopping, travel, sports
  • Charité has been certified as a family-friendly university and family-friendly company since 2007

Job Information

  • Salary group E13 according to TVöD- VKA- K. The classification is based on qualification, the respective experience level is calculated from the years of professional experience. The annual salary (gross) is given for a full-time position without annual bonus, allowances and additional services. You can find the collective agreement here
  • The working time is part-time with 25 hours per week
    At our company 30 days of vacation are standard
    The position is limited to 3 years, as it is tied to the project duration
    The application deadline is on: 28.02.2025
    Reference number: 4361

Application

 

Apply using our online tool and become part of the Charité.

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For further questions please contact:

Dr. med. Frank Dubois
frank.dubois@charite.de

 

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.