Working at the Charité
The group of Dr. Frank Dubois is looking for highly motivated Research Associate (PhD candidates) interested in investigating how cancer cells change the 3D genome to hijack gene regulation for aberrant expression of oncogenes from high-level genomic amplifications. The bioinformatics part of the project will involve whole genome sequencing and epigenetic analysis of several hundred tumor samples from breast and lung cancer patients.
Job Overview
The lab is a young group funded by a Max Eder Grant of the German Cancer Aid and is located at the Institute of Pathology at Charité Campus Mitte. We have extensive experience in both computational and experimental approaches. The successful applicant will work closely with an international and interdisciplinary group, including clinicians, bioinformaticians, and biologists. The environment provides many opportunities to learn new skills and we are deeply committed to excellent mentorship. A wealth of basic science and clinical collaborations in Berlin enable the pursuit of questions with translational potential. For more information please see www.duboislab.org.
Your responsibilities may include, but are not limited to, the following activities:
- Analysis of sequencing data from short-read and long-read WGS, methylation, HiC, ATAC, ChIP, and RNAseq data starting from the raw data/ fastq files
- Identify significantly recurrent genomic changes in cohorts of tumor samples, developing generalizable tools and pipelines in the process
- Work with the other group members and collaborators in Berlin and other institutions across the world
- Contribute to all levels of the research you are engaged including experimental design, data analysis, visualization, and writing
- Scientific staff is given sufficient time to carry out their own scientific work in accordance with their employment relationship (in accordance with § 110 BerlHG)
Advantages at the Charité
- A highly professional collaboration within a motivated and interdisciplinary team
- A future-oriented, varied and challenging job with high levels of personal responsibility and personal freedom of action
- Inter-cultural team events, well-structured onboarding with friendly colleagues
- Extensive free continuing education and training opportunities up to and including university studies
- Discounts on various offerings for employees, for example shopping, travel, sports
- Charité has been certified as a family-friendly university and family-friendly company since 2007