PhD student (d/f/m) Gastroenterology / Infectiology / Rheumatology

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Work time
part-time

Start date
Ab sofort

Employment period
limited

Application deadline
02.03.2025

Deployment location Charité
Campus Benjamin Franklin, Steglitz

Jobcode
4328

Salary group
E13

Working at the Charité

The SFB "Dynamic Hydrogels at Biointerfaces" investigates the key physicochemical parameters that determine protective hydrogel function at biological interfaces in health and define abnormalities in disease for prospective development of novel therapeutic strategies. This specific project will work on the biophysical and biochemical properties of the intestinal mucus layer, as well as their modulation by microbiota as key regulators of intestinal barrier function.

Job Overview

In ccoperation with the Weinhart group from the FU Berlin, the following main research aims will be addressed:
Biofabrication and characterization of mucus producing in vitro models of human small intestine
Evaluation of biophysical and biochemical stimuli on mucus composition and properties
Determine the role of secreted mucus for intestinal barrier function
Analysis of disease specific changes of barrier function in relation to mucus properties, composition and intestinal microbiota
Therefore, self-renewing, mucus producing in vitro models comprising 2D and 3D epithelial cultures, both derived from human intestinal 3D organoids, will be applied to identify mucus related features of the human intestinal epithelial barrier of healthy and diseased tissue samples
Our group is located at the Campus Benjamin Franklin and provides a state-of-the-art immunological and molecular research lab as well as a comprehensive technical infrastructure
Additional information about the work group can be found on our web page
In accordance with §110 BerlHG, the employee is given time for his/her own academic qualification

Required

Applicants should hold a master's degree in biology / life sciences, preferably with an background in immunology, cell or molecular biology
Candidates should be self-motivated and be able to pursue research projects independently as well as in collaborations
Good command of written and oral English is essential

Advantages at the Charité

A highly professional collaboration within a motivated and interdisciplinary team
A future-oriented, varied and challenging job with high levels of personal responsibility and personal freedom of action
Inter-cultural team events, well-structured onboarding with friendly colleagues
Extensive free continuing education and training opportunities up to and including university studies
Discounts on various offerings for employees, for example shopping, travel, sports
Charité has been certified as a family-friendly university and family-friendly company since 2007

Job Information

Salary group E13 according to TVöD- VKA- K. The classification is based on qualification, the respective experience level is calculated from the years of professional experience. The annual salary (gross) is given for a full-time position without annual bonus, allowances and additional services
The working time is part-time with 25 hours per week
At our company 30 days of vacation are standard
The position is limited until 31.12.2028, as it is tied to the project duration
The application deadline is on: 02.03.2025
Reference number: 4328

Application

Apply using our online tool and become part of the Charité.

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For further questions please contact

Dr. Rainer Glauben
rainer.glauben@charite.de

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.