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Research Assistant (Postdoc, d/f/m) Computational Immunology

Specialty
Immunology

Charite Kampagne Englisch Discovery 2
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Work time
full-time

Start date
15.01.2027

Employment period
limited

Application deadline
11.12.2026

Deployment location Charité
Campus Virchow-Klinikum, Wedding

Jobcode
8577

Salary group
E13

 

Working at Charité

The Joint Department: Infectious Diseases, Respiratory Medicine and Critical Care Medicine conducts translational research on infectious and respiratory diseases. The Buchauer Group is working in computational immunology and develops tools for the analysis of omics and flow data. The Gröschel Group focuses on innovative approaches to the diagnosis, treatment, and prognosis of tuberculosis, as well as the development and evaluation of AI tools for clinical practice. Our young, interdisciplinary team offers rich opportunities for professional development within a collaborative working environment.

As part of the DFG Research Unit "Hospital-acquired Infections – Unraveling Protective and Predisposing Factors for the Development of Novel Prophylactic Strategies (HAI)" based at our department, the Sander, Gröschel and Buchauer Groups are investigating the role of T cells in nosocomial infections. While the role of T cells in viral infections is relatively well understood, their function in bacterial infections—particularly in the transition from colonization to invasive disease—remains unclear. Within this project, we aim to investigate the interplay between existing T-cell immunity, bacterial virulence markers, and the occurrence of nosocomial infections by characterizing pathogen-reactive T cells from patient cohorts, including single-cell sequencing and TCR sequencing, alongside pathogen sequencing and bioinformatic analyses. The project bridges basic and applied research, aiming to improve the diagnostics and prevention of hospital-acquired infections. To drive this effort, we are looking for a motivated research assistant (postdoc) to carry out the project and analyze the collected data.

Overview of the position

  • You will be responsible for all computational and bioinformatics analyses within the subproject. This includes:
    • Processing and analysis of single-cell sequencing data
    • TCR repertoire analysis
    • Bacterial genomics (whole-genome and metagenome sequencing) and within-host evolution
    • Integrative statistical modeling of host, pathogen, and clinical data
  • You will develop and test novel methods for TCR and single cell RNA sequencing data
  • You will assist with data management
  • You will contribute to the preparation of project publications and present the project results at scientific conferences and internal project events
  • You will be employed as a research assistant: According to §110 (4), sentence 3 of the Berlin Higher Education Act (BerlHG), research assistants are entitled to an appropriate amount of time during working hours for their own scientific professional development

What we are looking for

  • You hold a scientific university degree (Master’s, Diplom, or equivalent) in bioinformatics, computational biology, computer science, physics, mathematics, statistics, or the life sciences with a quantitative focus, which is recognized in Germany (see anabin - https://anabin.kmk.org).
  • You hold a Ph.D. in one of the aforementioned disciplines or a related field.
  • You have in-depth knowledge and practical experience in at least one of the following areas: single-cell omics analysis, immune repertoire (TCR) analysis, or bacterial genomics, as well as a willingness to quickly familiarize yourself with the other areas.
  • You have very strong programming skills in Python and/or R; ideally, you have experience with Linux, high-performance computing (HPC), version control (Git), and workflow management.
  • You have a solid understanding of statistics and machine learning.
  • Basic knowledge of immunology and/or microbiology is a plus.
  • You have already gained experience in scientific writing and publishing in international journals.
  • You have knowledge of research data management (FAIR principles) and handling pseudonymized patient data.
  • You have excellent written and oral communication skills in English. Knowledge of German is a plus.
  • You have the ability to conduct independent, structured, and goal-oriented scientific work.
  • You are able to work in interdisciplinary (clinical, experimental, and computational) teams.
  • You are able to organize yourself and others and have a strong sense of responsibility.

Charité offers you

  • Highly professional work environment in motivated and interdisciplinary teams
  • A future-oriented, varied and demanding position with a high grade of personal responsibility and personal decision making opportunities
  • Intercultural team events, well structured onboarding phase with kind team members
  • Extensive offers for inhouse training and professional development as well as further qualifications
  • Special offers in the areas of shopping, travel and sports
  • Bike leasing via "JobRad" possible, bike repair workshop with subsidised price conditions for employees available
  • Additional pension program with a company wide pension scheme
  • Certification as a family friendly university and company since 2007 - You may find further information here

Information regarding the position

  • Paygrade E13 according to TVöD VKA-K. Here you'll find all the information about salary and the collective bargaining agreement
  • Full-time position (38.5 hours per week); part-time work is possible upon agreement
  • The position is limited until 30.09.2030 as it is tied to the project duration
  • 31 days of paid vacation per year
  • The application period ends on:11.12.2026
  • Position ID: 8577

Application

 

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.

For data protection reasons, we only accept applications via our application portal. The contact details provided below are intended solely for inquiries.

Apply now

If you have questions, please contact:

Prof. Dr. Lisa Buchaucher, lisa.buchauer@charite.de

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.