Work time
part-time
Start date
01.02.2027
Employment period
limited
Application deadline
26.11.2026
Deployment location Charité
Campus Virchow-Klinikum, Wedding
Jobcode
8376
Salary group
E13
Working at Charité
The Joint Department: Infectious Diseases, Respiratory Medicine and Critical Care Medicine conducts translational research on infectious and respiratory diseases. The Sander Research Group investigates host-pathogen interactions and the mechanisms of protective immunity to develop and optimize novel vaccines and antimicrobial therapies for infectious diseases. The Gröschel Research Group focuses on innovative approaches to the diagnosis, treatment, and prognosis of tuberculosis, as well as the development and evaluation of AI tools for clinical practice. Our young, interdisciplinary team offers rich opportunities for professional development within a collaborative working environment.
As part of the DFG Research Unit "Hospital-acquired Infections – Unraveling Protective and Predisposing Factors for the Development of Novel Prophylactic Strategies (HAI)" based at our department, the Sander, Gröschel and Buchauer Research Groups are investigating the role of T cells in nosocomial infections. While the role of T cells in viral infections is relatively well understood, their function in bacterial infections—particularly in the transition from colonization to invasive disease—remains unclear. Within this project, we aim to investigate the interplay between existing T-cell immunity, bacterial virulence markers, and the occurrence of nosocomial infections by characterizing pathogen-reactive T cells from patient cohorts, including single-cell sequencing and TCR sequencing, alongside pathogen sequencing and bioinformatic analyses. The project bridges basic and applied research, aiming to improve the diagnostics and prevention of hospital-acquired infections. To drive this effort, we are looking for a motivated PhD candidate to perform wet-lab work and contribute to bioinformatic analyses.
Overview of the position
- You will be responsible for processing clinical samples, including performing advanced cellular immunological assays (cell isolation, T-cell stimulation, MACS- and FACS-based cell isolation and sorting, single-cell sequencing preparation, functional T-cell assays)
- You will handle sample preparation for next-generation sequencing (NGS)
- You will contribute to the bioinformatic analysis of data in close collaboration with the project’s Postdoc
- You will collaborate with clinical project partners for sample collection and with core facilities for cell sorting and sequencing
- You will contribute to drafting manuscripts and presenting research findings at national and international conferences
- You will be employed as a research assistant: According to §110 (4), sentence 3, the BerlHG provides that research assistants are to be allotted an appropriate amount of time during their working hours for their own academic development
What we are looking for
- You hold a degree (Master's level or equivalent) in molecular biology (or a related field) and have sound knowledge of immunology, microbiology, or molecular cell biology, combined with a strong interest in infectious diseases and host-pathogen interactions.
- Ideally, you have already gained practical experience in cell isolation and flow cytometry.
- Ideally, you possess basic practical or conceptual experience with single-cell sequencing technologies or have a strong interest in learning and applying these methods.
- You have the ability to perform basic bioinformatic analyses of single-cell sequencing datasets, or a strong willingness to acquire these skills.
- You combine keen intellectual curiosity with a strong sense of responsibility.
- You have the ability to work both independently and collaboratively in an interdisciplinary environment alongside laboratory staff, core facility personnel, and bioinformaticians.
- You possess very good written and spoken English communication skills.
Charité offers you
- Highly professional work environment in motivated and interdisciplinary teams
- A future-oriented, varied and demanding position with a high grade of personal responsibility and personal decision making opportunities
- Extensive offers for inhouse training and professional development as well as further qualifications
- Special offers in the areas of shopping, travel and sports
- Additional pension program with a company wide pension scheme
- Certification as a family friendly university and company since 2007 - You may find further information here
- Consideration of personal wishes regarding the weekly working schedule
Information regarding the position
- Pay Grade E13, TVöD-K. Here you will find all the information about salary and the collective bargaining agreement
- Part-time position with 25 hours per week
- The position is limited until 30.09.2030, as it is tied to the project duration
- 31 days of paid vacation per year
- The application period ends on 26.11.2026
- Position ID 8376
Application
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
For data protection reasons, we only accept applications via our application portal. The contact details provided below are intended solely for inquiries.
Apply nowIf you have questions, please contact:
matthias.groeschel@charite.de
More information
Data protection information
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Additional information
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.