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Postdoctoral Researcher (d/m/f) - Computational Biology / Bioinformatics – Proteomics and Complex Biological Data

Specialty
Biochemistry, Molecular biology

Charite Kampagne 1350x900 5 Entdeckung 1
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Work time
full-time

Start date
ab sofort

Employment period
limited

Application deadline
11.09.2026

Deployment location Charité
Campus Charité Mitte

Jobcode
8122

Salary group
E13

 

Working at Charité

Working at the Charité

The Ralser Lab at Charité – Universitätsmedizin Berlin investigates how cells control their metabolism on a large scale. With a focus on yeast, we use functional genomics and advanced mass spectrometry to study how genes and metabolic pathways interact. Our goal is to uncover basic principles of metabolism that are relevant for cancer, immunology, metabolic diseases, and clinical diagnostics.

As part of the ImmunoPreCept Cluster of Excellence, we are developing approaches to extract biological information from complex, large-scale proteomics datasets by combining them with genomics and computational methods. The project brings together method development, quantitative data analysis, and biological discovery, using unique datasets from microbial systems, microbiomes, and patient cohorts.

Overview of the position

Position Overview

We are looking for a computational biologist / bioinformatician with a strong interest in quantitative biology and mass spectrometry-based proteomics.

A major focus of the project will be the development of computational and statistical approaches for analyzing complex proteomics datasets. You will investigate how experimental design, sample complexity, mass spectrometry acquisition, and data-processing strategies influence quantitative results and their biological interpretation.

The project provides access to exceptional large-scale datasets and biological resources, including proteomic datasets from microbial communities, gut microbiomes, patient cohorts, and yeast strain libraries. These systems will provide opportunities to apply and further develop computational approaches in areas ranging from microbial physiology and systems biology to host–microbe interactions and inflammatory disease.

You will:

  • Generate systematic proteomic datasets as part of a collaborative team effort
  • Develop and apply statistical and quantitative approaches to extract biological information from high-dimensional data
  • Integrate proteomics data with other biological data, e.g. genomics data, and clinical information
  • Collaborate closely with mass spectrometry experts, experimental scientists, computational biologists, immunologists, and clinicians
     

You will be employed as a postdoctoral researcher: According to §110 (4), sentence 3, the BerlHG provides for postdoctoral researchers to be allotted an appropriate amount of time during their working hours for their own academic development.

What we are looking for

What we are looking for

  • PhD in bioinformatics, computational biology, systems biology, or related quantitative field
  • Experience in the analysis of biological data, especially mass spectrometry-based proteomics data
  • Strong knowledge of statistical and quantitative methods for analyzing complex, high-dimensional datasets
  • Good understanding of the principles of biochemical methods, including mass spectrometry
  • Good programming skills in Python and R
  • Strong communication skills, ability to work in interdisciplinary teams, and proven publication track record
  • Ability to work independently while collaborating across research groups

Charité offers you

What we are offering

  • Access to exceptional large-scale datasets and cutting-edge mass spectrometry technologies
  • A research environment, combining computational method development, quantitative biology, and biological discovery
  • Close collaboration with experts in proteomics, mass spectrometry, systems biology, microbiology, immunology, and clinical research
  • Opportunities to contribute to translational research
  • Comprehensive training and professional development opportunities
  • Interdisciplinary collaboration within the ImmunoPreCept Cluster of Excellence at one of Europe's largest research-intensive medical universities
  • High degree of scientific independence and scope to develop your own research directions
  • An excellent track record of alumni progressing to independent group leader roles and leadership positions in academia and industry

Information regarding the position

  • Paygrade E13 according to TVöD VKA-K. Your job grade depends on your job qualification whereas the experience level depends on the number of working years. The yearly gross salary is hereby provided based on a full time position excluding yearly bonus and additional pay. You may find further information here
  • Working hours full-time with 38.5 hours per week.
  • The position is limited until 30.06.2028, as it is tied to the project duration
  • 30 days of paid vacation per year
  • The application period ends on: 11.09.2026
  • Position ID: 8122

Application

 

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.

For data protection reasons, we only accept applications via our application portal. The contact details provided below are intended solely for inquiries.

Apply now

If you have questions, please contact:

For any inquiries, please visit our web page (https://ralser.group/), or contact Prof. Dr. Markus Ralser (markus.ralser@charite.de) or Dr. Lisa Schlünz-Kahl (lisa.kahl@charite.de). 

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.