Specialty
Internal medicine
Work time
part-time
Start date
ab sofort
Employment period
limited
Application deadline
13.08.2026
Deployment location Charité
Campus Charité Mitte; Campus Virchow-Klinikum, Wedding; Campus Benjamin Franklin, Steglitz
Jobcode
7859
Salary group
E13
Working at Charité
The Collaborative Research Center/Transregio (CRC/TRR) 241 is inviting applications for up to 3 doctoral (PhD) positions (65% TV-L E13) across a broad range of participating disciplines and research areas in the field of mucosal immunology of chronic inflammatory bowel diseases.
In Berlin, CRC/TRR 241 is coordinated by Charité – Universitätsmedizin Berlin and includes collaborative projects with the Max Delbrück Center for Molecular Medicine (MDC) and the German Rheumatism Research Centre (DRFZ, Leibniz Institute).
CRC/TRR 241 is currently in its third funding period and focuses on the interaction between the intestinal barrier (epithelium) and the immune cell compartment of the lamina propria. The aim is to gain a deeper understanding of these interactions in order to better understand the diseases and their subtypes, and ultimately to develop novel therapeutic approaches.
CRC/TRR 241 comprises projects investigating the immunology of defined cell populations in the intestine, as well as projects with a strong translational focus. During its first two funding periods, CRC/TRR 241 established a patient cohort that has been comprehensively characterized clinically, endoscopically, and at the molecular level. This resource is available to all research projects within CRC/TRR 241.
Further information on the TRR 241 can be found here.
Overview of the position
PhD positions:
AG Klose: Impact of epithelial dysfunction on neuro-immune crosstalk in IBD. PhD student with a background in immunology, neuroscience, or epithelial cell biology for a project on the enteric nervous system and mucosal immunology in relation to colitis.
AG Stehle: The role of the γ-chain cytokines-STAT5 axis for epithelial barrier function and intestinal inflammation. PhD student to investigate how the γ-chain cytokine–STAT5 signaling axis regulates immune–epithelial communication and drives intestinal inflammation in inflammatory bowel disease. The project combines cutting-edge approaches, including spectral flow cytometry, single-cell and bulk RNA sequencing, conditional knockout mouse models, and human organoid co-cultures to uncover disease mechanisms from mouse to human. Ideal for candidates interested in immunology, inflammation, and advanced experimental technologies.
AG Triantafyllopoulou: Reprogramming of innate immune - tissue units in inflammatory bowel disease. PhD student to investigate how macrophages and innate lymphoid cells shape immune responses and tissue homeostasis in inflammatory bowel disease. The project will explore the cellular interactions that drive chronic intestinal inflammation and identify mechanisms that promote tissue repair and barrier function.
What we are looking for
We seek highly motivated PhD students and postdoctoral researchers who
Application documents required (as a single PDF in English):
Charité offers you
Specific Offers for PhD Students
We place great value on a respectful and appreciative working environment, which is a central part of our team culture and actively practiced. Flexible remote work arrangements by agreement, as well as 30 days of vacation (plus days off on December 24 and 31), support a good balance between work and family life.
Advantages at Charité
Information regarding the position
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
For data protection reasons, we only accept applications via our application portal. The contact details provided below are intended solely for inquiries.
Apply nowIf you have questions, please contact:
Fr. Birgit Röders
Email: birgit.roeders@charite.de
Phone: +49 (0)30 450 514135
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.