Bioinformatician / data scientist in functional cancer genomics
Work time
part-time
Start date
Ab sofort
Employment period
limited
Application deadline
08.02.2026
Deployment location Charité
Campus Benjamin Franklin, Steglitz
Jobcode
6302
Salary group
E13
Working at Charité
The project focuses on defining molecular networks that overcome cellular senescence, a nature-given protective mechanism which blocks proliferation of precancerous cells. By using global transposon mutagenesis, we induce malignant transformation in healthy B-cells with a wild type or senescence-incompetent genomic background. Sequencing the pool of transposon insertions allows us to dissect the driving force of lymphomagenesis and senescence-inactivating mechanisms. We further study how this mutational network evolves under therapy to find molecular dependencies which can overcome drug resistance. We deploy advanced in vitro and in vivo model systems, genetic perturbations, lineage tracing and single-cell technologies to study the distinct routes of tumor evolution and modes of therapy resistance.
Overview of the position
- We are seeking a highly motivated bioinformatician / data scientist to join our research group focused on functional cancer genomics and therapy resistance
- The position is located at the hematology and oncology research lab at the Charité Berlin (Research group of Dr. Maja Milanovic), with interdisciplinary framework and close collaboration between wet-lab and computational scientists
- The vibrant and internationl scientific environment offers numerous interactions with other groups with expertise in cancer biology, immunology, bioinformatics and system biology, as well as various opportunities for advanced scientific education, training and networking
- This 50% position can be supplemented to a fulltime position by a partner laboratory for cancer research that is technologically well aligned to the project described.
Your responsibilities will be:
- Conduct bioinformatics analysis of bulk and single cell RNAseq, DNA sequencing, transposon insertions and CRISPR screen libraries using existing bioinformatic packages and pipelines
- Integrate these datasets with own or public data of molecular, phenotypic (e.g. histology, FACS), drug screening, and clinical information
- Participate in setting up bioinformatics platforms and developing new computational pipelines
- Ensure proper scientific documentation
What we are looking for
- Years of professional experience in computational biology, bioinformatics, systems biology, data science or related subjects with demonstrated interest in life sciences
- Extensive experience in scientific computing using R and Python for data science
- Proactive working attitude and willingness to learn, develop and apply state-of-the-art computational approaches
- Team spirit and excellent communication skills in multifunctional teams with experts in different areas
- Fluent command of written and spoken English
Charité offers you
- We are seeking candidates to join our research group focusing on functional cancer genomics and therapy resistance
- The position is based in the Hematology and Oncology Research Laboratory at Charité in Berlin (research group of Dr. Maja Milanovic), which is characterized by an interdisciplinary approach and close collaboration between wet-lab and computational scientists
- The dynamic and international scientific environment offers numerous opportunities for interaction with other groups with expertise in cancer biology, immunology, bioinformatics, or systems biology, as well as various opportunities for scientific training and networking
- This 50% position can be complemented to a full-time position through a partner cancer research laboratory that is technologically well aligned with the described project
- In accordance with §110 of the Berlin Higher Education Act (BerlHG), time will be provided for the candidate’s own scientific qualification
Information regarding the position
- Paygrade E13 according to TVöD VKA-K. You may find further information here
- Working hours will be part-time with 19,25 hours per week
- The position is limited until 31.12.2028, as it is tied to the project duration
- 30 days of paid vacation per year
- The application period ends on: 08.02.2026
- Position ID: 6302
Application
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
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More information
Data protection information
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Additional information
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.