Postdoctoral Scientist (d/f/m) in Regulatory Genomics

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Arbeitszeit
Vollzeit

Eintrittsdatum
01.01.2025

Dauer der Anstellung
Befristet

Bewerbungsfrist
18.11.2024

Einsatzort Charité
Campus Virchow-Klinikum, Wedding

Jobcode
3864

Entgeltgruppe
E13

Company describtion

The mission of the Berlin Institute of Health at Charité (BIH) is medical translation: transferring biomedical research findings into novel approaches to personalized prediction, prevention, diagnostics and therapies and, conversely, using clinical observations to develop new research ideas. The aim is to deliver relevant medical benefits to patients and the population at large. Since 2021 the BIH has been integrated into Charité as its so-called third pillar.

For the workgroup Dr. Daniel Ibrahim starting from the 01.01.2025 and limited until 31.12.2027 we are looking for a Postdoctoral Scientist (f/m/d) in Regulatory Genomics in full-time (39h/week).

We are interested in how the interplay between enhancers within regulatory domains influences cell-type specific gene expression. Based on the skills and interest of the candidate, we have more bioinformatics or experimentally heavy projects available.

We are using a synthetic biology derived workflow to studying gene regulation. Through combination of methods from microbiology with integrase-based genome engineering for mESCs and human iPSCs we are able to synthesize any DNA sequences of dozens to hundreds of kb and integrate them site-specific into the mESCs and human iPSCs. By combining this genome engineering approach with cell, organoid, and in vivo model systems

What you can expect

Stem cell culture
Assembly of synthetic BACs in yeast and targeting into mammalian stem cells
Functional genomics (ChIP/RNA/ATAC-seq, Cut & Tag etc.)
Bioinformatic analysis of functional genomic data
Design of synthetic gene regulatory domains (no prior experience necessary)
Being part of the scientific endeavour (incl. reading/writing of papers, experimental design and discussions)

What you bring along

PhD in Molecular biology, Biochemistry, and related fields
Ideally a background in gene regulation, chromatin biology or epigenetics
Proficiency in basic bioinformatic analyses
Fluent English (C1- level or similar)

What we offer you

A varied job in a forward-looking research institute
Pay group E13 TVöD VKA-K. The classification is based on qualifications, the respective experience level is calculated on the basis of professional experience. The annual salary (gross) is stated for a full-time position without special or additional payments. The collective agreement can be found here.
Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
Flexible working hours
30 vacation days per year (with a five-day week)
Various support offers to balance work and family life (childcare, cooperation with voiio)
Very good training and further education opportunities
Mobile citizens' office on site
Corporate benefits (travel, leisure, shopping, etc.), Charité Gympass, bicycle leasing or abonnement (JobRad, mylo)
Very easily accessible and attractive workplace at the Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin

We live diversity!

We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnic and social origin, religion and ideology, disability, age, sexual orientation and identity. Applications from women are expressly encouraged. Severely disabled and equivalent applicants will be given special consideration if they have the same qualifications and suitability.
We believe that diverse teams representing a wide range of experiences, perspectives and backgrounds enrich our research and work.

Please submit your application via our online application form with a letter of motivation, curriculum vitae (without photo, without age statement and without information about your marital status) and other relevant attachments (such as employer references, degree certificates, etc.) by November 30, 2024, quoting the reference number 3864.

Note: If you have a foreign degree, please submit proof of recognition of your degree in Germany with your application. The proof can be obtained via the anabin database. Please note that it may be necessary to obtain a certificate assessment from the ZAB. You can find more information here.

Proof of measles immunity / measles vaccination is a prerequisite for employment for those born after 1970.

You can find more information about BIH here.

Application

Apply using our online tool and become part of the Charité.

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Contact person

If you have any technical questions about the job posting, please contact Mr. Dr. Daniel Ibrahim (e-mail: daniel.ibrahim@bih-charite.de).

More information

Data protection information

The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.

Additional information

Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.