PhD student in experimental cancer research
Start date
schnellstmöglich
Application deadline
23.01.2026
Jobcode
6272
Salary group
E13
Working at Charité
We are seeking a highly motivated doctoral candidate to explore how cancer cells modify the 3D genome to manipulate gene regulation, leading to abnormal oncogene expression caused by high-level genomic amplifications. Using CRISPR-based methods, you will model recurring oncogenic changes in the 3D genome observed in breast and lung cancers to identify potential candidates for new cancer treatments.
The lab is funded by a Max Eder Grant from the German Cancer Aid and is based at the Institute of Pathology at Charité Campus Mitte. We have broad experience in both computational and experimental methods. You will collaborate closely with an international, interdisciplinary group that includes clinicians, bioinformaticians, and biologists. Numerous basic science and clinical collaborations in Berlin allow us to explore questions with translational potential. For more information, please visit www.duboislab.org and feel free to reach out via email (frank.dubois@charite.de).
Overview of the position
Your responsibilities may include, but are not limited to, the following activities:
- Analysis and interpretation of variant calls from WGS and epigenetic analysis of cell lines
- CRISPR perturbations of cell lines and validation experiments of cell growth and oncogene expression
- Work with the other group members and collaborators in Berlin and other institutions across the world
- Contribute to all levels of the research you are engaged including experimental design, data analysis, visualization, and writing
You are employed as a research assistant: According to §110 (4), sentence 3, the BerlHG provides for a reasonable amount of time within working hours for research assistants to pursue their own further scientific qualification.
What we are looking for
- You hold a Master's degree in Biology, Biochemistry, Bioengineering, or a related field
- You have experience in experimental biology (cell culture, molecular biology, biochemistry)
- Experience in functional genomics (CRISPR perturbation) is an advantage
- You possess strong intrinsic motivation, scientific curiosity, organizational skills, and a keen interest in learning about new technologies
- Good written and spoken communication skills in English complete your profile
Please send us a cover letter, your CV, certificates, a list of publications and contact information for three references.
Charité offers you
- We offer a friendly, collegial, and fast-paced environment where scientific excellence is pursued, clinically relevant questions are investigated, and every team member is supported
- Excellent supervision and numerous opportunities to develop new computer-based and experimental skills
- Work on clinically relevant research questions with translational potential
- Discounts on many employee offers in the areas of shopping, travel, and sports
- Certified as a family-friendly university and family-friendly employer since 2007 – further information can be found here
Information regarding the position
- Paygrade E13 according to TVöD VKA-K. Your job grade depends on your job qualification whereas the experience level depends on the number of working years. The yearly gross salary is hereby provided based on a full time position excluding yearly bonus and additional pay. You may find further information here
- Working hours are part-time with 25 hours per week
- The position is limited until 31.12.2027, as it is tied to the project duration
- 30 days of paid vacation per year
- The application period ends on: 23.01.2026
- Position ID: 6272
Application
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
Apply using our online tool and become part of the Charité.
Apply nowIf you have questions, please contact:
Dr. med. Frank Dubois
frank.dubois@charite.de
More information
Data protection information
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Additional information
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.