PhD Position (d/w/m) about Sympathetic Signaling in Polytrauma Research
Specialty
Orthopedics and trauma surgery
Work time
part-time
Start date
Zum nächstmöglichen Zeitpunkt
Employment period
limited
Application deadline
04.01.2026
Deployment location Charité
Campus Charité Mitte
Jobcode
6001
Salary group
E13
Working at Charité
Our interdisciplinary research group investigates the interaction between the central nervous system (CNS) and bone, focusing on the role of adrenergic signaling. We study how different kinds of CNS trauma, such as traumatic brain injury and spinal cord injury, interact with bone fractures. Investigating how the early metabolic and inflammatory trauma response is regulated by sympathetic signaling, we aim to develop novel therapies to improve clinical outcomes for patients with complex trauma. Benefits: Access to cutting-edge research facilities, including murine intensive care unit; Strong career development support, including conferences, workshops, and publications; FELASA course to acquire certified knowledge in animal handling; Exciting opportunity to contribute to innovative research with significant clinical implications
Overview of the position
· Investigating the impact of adrenergic signaling on the body’s acute response to combined injuries
· Design and conduct in vivo experiments using an advanced murine intensive care unit to model the patient situation
· Perform serum and organ analysis (ELISA, qPCR, FACS) for stress hormones, metabolic markers, cytokines and immune cells after polytrauma
· Advance a project in polytrauma research and communicate your findings (publications, presentations)
· Collaborate with multidisciplinary teams, including experts in bone biology and trauma research
· According to Section 110 BerlHG, the employee is provided with time for their own academic qualifications
What we are looking for
• A Master's degree in Biology, Biochemistry, Pharmacology, Neuroscience, or a related field
• Strong background in molecular biology, metabolism and immunology
• Hands-on experience with standard molecular biology techniques
• Excellent problem-solving skills and attention to detail and reliability
• Strong communication and teamwork skills, as well as the ability to work independently
• Enthusiasm for interdisciplinary research and a keen interest in polytrauma research
Desirable Skills:
• Experience with animal handling and in vivo experiments
• Experience with Flow Cytometry
• Advanced knowledge in the analysis of large data sets
• Familiarity with statistical analysis and data interpretation
Charité offers you
Information regarding the position
Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.
Apply using our online tool and become part of the Charité.
Apply nowIf you have questions, please contact:
denise.jahn@charite.de
The Charité would like to point out that personal data is stored and processed at various locations at the Charité premises (e.g. specialty department, personnel representatives, HR department) as part of and for the purposes of the application process. Furthermore, the data may be transferred or processed within the group and to external bodies (e.g. authorities) to protect legitimate interests. By submitting your application, you agree to our data protection policy and terms of use for application procedures, which you can find here.
Charité – Universitätsmedizin Berlin makes its personnel decisions based on suitability, ability and professional performance. The Charité aims to increase the proportion of women in management positions and therefore strongly encourages women to apply. Women with equivalent qualifications will be given priority within the scope of legal possibilities. Applications from people with a migration background who meet the recruitment requirements are expressly encouraged. Severely disabled applicants with equal qualifications will be given preference. A police good-conduct certificate, in some cases an extended good-conduct certificate, is required at the time of recruitment. Unfortunately, application documents can be returned only if a sufficiently stamped envelope is enclosed. Any incurred travel expenses cannot be reimbursed.